MYTH OF THE MONTH

 

 

 

 

 

AUGUST 2017

MYTH: Cancer is a man-made disease

TRUTH:

 

JULY 2017

MYTH: Chemotherapy does not work 97% of the time.

TRUTH: This falsehood originates from an Australian review of studies published in 2004 which stated that the “5-year survival benefit attributable solely to cytotoxic chemotherapy in adult malignancies” is only a little over 2%.1 The review of studies can be found here. Although this review was intended to evaluate the contribution of chemotherapy to cancer survival rates the researchers evaluated a scant 22 types of cancer2 (there are over 100 kinds of cancers), and of those most of them are either not typically treated with chemotherapy or use chemotherapy only as a secondary treatment, not the primary. On top of this the review also purposely omitted leukemias and most lymphomas, which are known to be very responsive to chemotherapy. For a review that was intended to evaluate the contribution of chemotherapy to survival rates the researchers clearly fell short. This was noted and questioned the following year by a group of oncologists3 who further noted that other flaws in the review included using only newly-diagnosed patients, omitting important information regarding adjuvant chemo treatments, and providing misinformation regarding some of the cancers evaluated. This group of oncologists went on to state "The contribution of this type of analysis, with pooling of all cancer patients, is questionable and potentially misleading."

1The Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies (Morgan, 2004)
2The cancers evaluated were: Anal, bladder, brain, breast, carcinoma of unknown primary site, cervical, colon, esophageal, head and neck, Hodgkin's disease, kidney, lung, malignant melanoma, non-Hodgkin's lymphoma, ovarian, pancreatic, protstate, rectal, soft tissue carcinoma, stomach, testicular, and uterine cancers.
3Clinical Oncology, June 2005, Volume 17, Issue 4, pp. 294, “The Contribution of Cytotoxic Chemotherapy to the Management of Cancer” (Mileshkin, et al)

 

JUNE 2017

MYTH: Pharmaceutical companies suppress the cure for cancer because they want to keep making money from the current products instead.

TRUTH: A number of cancer research organizations are non-profit entities, which means they have nothing to gain and everything to lose if they suppress a known cure for cancer. This includes well-known organizations such as the American Cancer Society, The Breast Cancer Research Foundation, The Cancer Research Institute, Memorial Sloan Kettering Cancer Center, and St. Jude Children's Research Hospital, just to name a few. Another thing to understand is that "cancer" is not a singular disease; the word "cancer" is actually an umbrella category for more than one hundred diseases which have a common trait: The uncontrolled growth of abnormal cells. Because cancer can occur in any type of body cell (bone, skin, lung, muscle, brain, blood, etc.) and each kind of cell has strengths and weaknesses different from the other kinds of cells, the different kinds of cancers each need different kinds of treatments in order to halt the disease process. Even cancers associated with the same location may differ from one another. For example, there are several main types of breast cancer (ER+/ER-, PR+/PR-, HER2+/HER2-, triple negative, and inflammatory breast cancers) and each type needs a specialized plan as the treatments are not interchangeable for all breast cancers. Because the umbrella term "cancer" is actually a collection of a large number of diseases with a common trait this means there cannot be one single cure for "cancer"; we would need to have a cure for each and every kind before we can say that "cancer" is cured. This is indeed a daunting task, and this is why we do not yet have a "cure for cancer." However, due to the rigorous research being performed on the roster of cancers we do have the fortune of having better therapies and treatments available for us to increase individual cure and survival rates.

 

MAY 2017

MYTH: Cancer is caused by too much acid in the body.

TRUTH: The concept of an acid diet began in the late 1800's when Marcelin Berthelo, a French Chemist, conducted experiments to calculate the amount of calories in food. To do this he placed food in a pressurized device called a bomb calorimeter and incinerated his samples leaving nothing but ash behind. Note that when water is mixed with the ash one can measure the pH level of the substance to decide whether it is acid or base, subsequently in 1912 a paper was published by H. C. Sherman and A.O. Gettler1 which classified foods as acid or base according to the pH levels taken from ash in the bomb calorimeter. A copy of the paper can be read here. Generally speaking, it found that fruits and vegetables tended to leave a base ash while meats and grains tended to leave an acidic ash. The current beliefs regarding “acidic” diet are based primarily on this paper, which isn't scientifically sound. Several years later Nobel prize winner Dr. Otto Warburg noted that oftentimes cancer cells have lower respiration and tend to live in an acidic environment giving rise to the theory that low oxygen and acidic environments cause cancer. 2 Since fermentation of sugar results in the formation of lactic acid he thought that the presence of this acid caused the cancer to form. Modern science, though, has shown that in reality it works the other way around, the cancer cells actually cause the acidity to appear. Let me explain: Just like any other body cell, cancer cells need a constant supply of oxygen and the ability to metabolize sugar for energy to survive. This is why tumors create their own system of blood vessels in order to transport oxygen and sugars to the tumor cells – if they did not, they could not grow. Although the tumor does create its own network of blood vessels they oftentimes outgrow their network before they can build more vessels, creating the need for them to have an alternative way to metabolize sugars in the meantime: Fermentation. Although the process of fermentation is not as efficient, it is all they have while additional blood vessels are being built; and this fermentation process creates the acidic environment around them. Because there are not enough blood vessels yet formed to flush this acid out the tumor site remain rather acidic until it forms enough new vessels. Ergo, it is not acid that causes the cancer, it is the cancer that causes the acid. Later research showed that neither the presence nor the lack of acidity affects the growth of cancer cells.3 Therefore, the bottom line is that acids do not cause cancer and do not advance a cancer's growth.

1The Balance of Acid-forming and Base-forming Elements in Foods, and its Relation to Ammonia Metabolism (H. C. Sherman, A. O. Gettler, 1912)
2The Prime Cause and Prevention of Cancer by Otto Warburg. 1966 annual meeting of Nobelists at Lindau, Germany
3Early and Late Apoptosis Events in Human Transformed and Non-transformed Colonocytes are Independent on Intracellular Acidification. (Wenzel, et al, 2004)

 

APRIL 2017

MYTH: Cancer needs a low-oxygen environment to thrive, therefore you should be treated with oxygen-based therapies to help cure your cancer.

TRUTH: This idea is based on a theory originated from Nobel prize recipient Dr. Otto Warburg, M.D. which was published in the 1930's. Dr. Warburg noted that cancer cells have a lower respiration rate than healthy cells, thus he theorized that cancer cells would die when exposed to greater concentrations of oxygen. Later, however, Dr. Warburg's theory was shown to be in error: In 1971 Dr. Moses Judah Folkman discovered that cancer tumors are actually dependent on angiogenesis – the formation of blood vessels connecting the tumor to the body's regular circulatory system – in order to thrive.1 Research based on Dr. Folkman's discoveries has shown that cancer tumors do, indeed, create their own network of blood vessels and will only thrive if these blood vessels are allowed to remain. A tumor's vessels are always connected directly to the body's regular circulatory system, thus the growing tumor is receiving the same level of oxygenation as the healthy cells, ergo it is thriving in an oxygenated environment. As a matter of fact, cancer treatments which block the process of angiogenesis in tumors (thus cutting off their oxygen supply) is one of the most effective methods in destroying tumors. Although Dr. Warburg was a brilliant doctor and scientist, he was clearly wrong on this one particular theory.

1Tumor Angiogenesis: Therapeutic Implications” (Folkman, M.D. 1971)

 

 

MARCH 2017

MYTH: Shark cartilage can cure cancer, this is why sharks do not get cancer.

TRUTH: Although preliminary research observed that powdered shark cartilage, when applied directly to a tumor, suppresses blood vessel growth in tumors (“angiogenesis”), thus suppressing tumor growth,1 oral consumption of shark cartilage does not give the same results. Shark cartilage molecules are too large to be absorbed through the digestive system, therefore it cannot enter the bloodstream and affect tumors. Clinical trials have proven that oral supplementation of shark cartilage does not suppress tumors.2 3 4 Also, it is proven that sharks, do indeed, develop cancer. 5

1Shark Cartilage Contains Inhibitors of Tumor Angiogenesis [tumor blood vessel formation] (Lee, Langer, 1993)
2Phase I/II Trial of the Safety and Efficacy of Shark Cartilage in the Treatment of Advanced Cancer. (Miller, 1998)
3Evaluation of Shark Cartilage in Patients with Advanced Cancer: A North Central Cancer Treatment Group Trial (Loprinzi, 2005)
4Chemoradiotherapy With or Without AE-941 in Stage III Non-small Cell Lung Cancer: A Randomized Phase III Trial. (Lu, 2010)
5Shark Cartilage, Cancer, and the Growing Threat of Pseudoscience. (Ostrander, 2004)